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Adadaro NPP 100

Adadaro NPP 100

Rs. 100.00
Product Details

Nandrolone Phenylpropionate (NPP) is a short-acting anabolic androgenic steroid (AAS), structurally related to testosterone. Compared to testosterone, it demonstrates reduced androgenic activity and a more pronounced anabolic effect. The phenylpropionate ester ensures a faster release into systemic circulation compared to decanoate esters, allowing for more flexible dosing schedules and improved tolerability in certain patient populations.

Indications & Mechanism of Action

AdaroNPP 100 is indicated for:

  1. Anemia of Chronic Disease & Renal Failure: Enhances erythropoiesis through stimulation of erythropoietin and direct bone marrow activity.
  2. Osteoporosis (Postmenopausal & Androgen-Deficient States): Promotes bone mineralization and calcium retention.
  3. Cachexia & Muscle Wasting Syndromes: Provides anabolic support in HIV/AIDS, cancer-related cachexia, or severe trauma recovery.
  4. Adjunct in Severe Burns & Post-Surgical Catabolic States.

Pharmacodynamics:

  • Binds to intracellular androgen receptors, inducing transcription of anabolic genes.
  • Enhances protein synthesis, nitrogen retention, and muscle mass.
  • Stimulates erythropoietin production, improving red blood cell mass.
  • Supports bone density via positive calcium balance.
  • Exhibits lower androgenic effects compared to testosterone, making it a preferred option in patients requiring long-term anabolic therapy.
Clinical& Safety

Contraindications:
• Known hypersensitivity to nandrolone or formulation excipients.
• History of breast carcinoma in males, androgen-dependent tumors, or suspected prostate cancer.
• Pregnant or breastfeeding women (Category X).
• Severe cardiac, renal, or hepatic dysfunction.
Potential Drug Interactions:
• May enhance the effects of anticoagulants such as warfarin.
• Alters glucose metabolism and may impact insulin or oral hypoglycemic dosing.
• Concurrent use with corticosteroids increases risk of edema and fluid retention.
Adverse Reactions:
• Endocrine: Suppression of endogenous testosterone, testicular atrophy, gynecomastia.
• Cardiovascular: Hypertension, fluid retention, dyslipidemia, increased thrombosis risk.
• Hepatic: Though less hepatotoxic than oral alkylated AAS, rare reports of hepatic dysfunction exist.
• Reproductive: Oligospermia, libido alterations.
• Other: Acne, oily skin, hair loss (in genetically predisposed individuals).
Dosage & Administration:
• Intramuscular (IM) injection into gluteal or thigh muscle.
• Typical therapeutic dosage: 50–100 mg every 3–4 days (adjusted to clinical response).
• Not for intravenous use.

Warnings & Precautions

1. Polycythemia: Regular hematologic monitoring is advised due to erythropoietic stimulation.
2. Prostate Monitoring: PSA testing and digital rectal exams are recommended in older men.
3. Cardiovascular Risk: Use with caution in patients with hypertension, CHF, or dyslipidemia.
4. Androgenic Effects in Women: May cause virilization (voice deepening, hirsutism, menstrual changes).
5. Psychiatric Considerations: Risk of mood swings, irritability, or behavioral changes with supratherapeutic use.

Storage & Handling

• Store at 15–30°C in a dry place.
• Protect from direct light and freezing.
• Inspect vials for particulate matter or discoloration before use.

Ethical& Regulatory

• Neurobolin 100 is strictly prescription-only and not intended for athletic performance enhancement.
• Subject to anti-doping regulations under WADA Prohibited List.
• Manufactured under compliance with GMP, FDA, and EMA guidelines.

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